My area and I would use:
I-376 East to I-76 South East (Turnpike)
Less than 2 hours and 125 miles.
Sarver, PA/Crystal River, FL/Shelocta, PA · W3TLN · FMCA 335149 · Mystic Knights of the Sea
2005 Suncruiser 38R · W24 chassis, no chassis mods needed · 2013 Honda Accord EX-L · 2008 Honda Odyssey EX-L