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 > 2019–2022 CORONAVIRUS PANDEMIC POSTINGS

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BCSnob

Middletown, MD

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Posted: 10/21/22 01:41pm Link  |  Quote  |  Print  |  Notify Moderator

This was the best info I found

Neutralization of SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, and BA.2
Cell Host & Microbe Volume 30, Issue 8, 10 August 2022, Pages 1093-1102.e3

MEXICOWANDERER

las peñas, michoacan, mexico

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Posted: 10/21/22 07:27pm Link  |  Quote  |  Print  |  Notify Moderator

Thank you Silversand & BC Bob

México isn't offering inoculations for Covid, booster or Delta.
And I haven't checked about the influenza serum but I've yet to encounter a boosted strength for the elderly. My option is to wait for 3 weeks or get a regular dose here but of a different source (Switzerland). I've already chosen the local jab for next week.
If memory serves me correctly that strain was H1N1

* This post was edited 10/22/22 07:19am by an administrator/moderator *

MEXICOWANDERER

las peñas, michoacan, mexico

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Posted: 10/22/22 12:44pm Link  |  Quote  |  Print  |  Notify Moderator

I've been curious about the effect of the totally unvaccinated skewing total "new" reported Covid cases.

For instance, California is reporting a pronounced spike in infections. Yet it has been publishing data that claims ten million people have not received even one dose of vaccine.

* This post was edited 10/22/22 01:29pm by an administrator/moderator *

silversand

Montreal

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Posted: 10/24/22 08:18am Link  |  Quote  |  Print  |  Notify Moderator

BC Snob wrote:

About the time the Moderna bivalent booster was available, we got boosted “naturally” (by BA.5, based upon prevalence). We’ll get the booster closer to the end of this year.

My wife had cold symptoms while I had 24hrs of bad flu symptoms and a week of residual cough.

Here is the preprint/publication I have found via google scholar on Moderna's mRNA-1273.222 (1:1 mix of mRNAs encoding the Wuhan-1 and BA.4/5 spike proteins).


Thanks BC! Heading over to read now....

Apparently, my wife and i are super-avoiders (or, we just have not been able to catch Covid; even snowbirding in Florida for more than 4 months this past winter); I read that appx 10% of the human population in various research have not yet "gotten it" (or, seem not to be vulnerable to "it") as yet. Of our 39 close contacts we talk to on a regular basis (daily to bi-daily), EVERYONE of them has had Covid (confirmed by test). Interestingly, the 39 say that "....you just know something is very, very different symptomatically from the flu or cold when you have Covid...".

Pianotuna:

....you mention what works against B 11.....did you mean BQ.1.1 ?

MexicoWanderer:

Cheers! I still cannot figure out why the GIS global flu tracker is not updating US flu data (??)


Silver
2004 Chevy Silverado 2500HD 4x4 6.0L Ext/LB Tow Package 4L80E Michelin AT2s| Outfitter Caribou

silversand

Montreal

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Posted: 10/24/22 08:25am Link  |  Quote  |  Print  |  Notify Moderator

MexicoWanderer wrote:

I've already chosen the local jab for next week.
If memory serves me correctly that strain was H1N1


....Mex: isn't the prevailing global flu strain presently the A (H3) ?

On edit: ....I am reading that the two flu shots recommended for 65+ years of age are: Fluad Quadrivalent, or Fluzone high-dose quadrivalent.... (https://www.goodrx.com/)

* This post was last edited 10/24/22 08:46am by silversand *   View edit history

pianotuna

Regina, SK, Canada

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Posted: 10/24/22 08:27am Link  |  Quote  |  Print  |  Notify Moderator

silversand,

B 1.1 but I may be wrong.


Regards, Don
My ride is a 28 foot Class C, 256 watts solar, 556 amp-hours of Telcom jars, 3000 watt Magnum hybrid inverter, Sola Basic Autoformer, Microair Easy Start.

silversand

Montreal

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Posted: 10/24/22 08:44am Link  |  Quote  |  Print  |  Notify Moderator

pianotuna wrote:

silversand,

B 1.1 but I may be wrong.


....OK....you may mean BQ1.1 as B (or, BA 1.1) seems to be extinct in the EU, Canada, Mexico, USA and even Japan. The new BQ animal has reached appx 10% in the USA presently (varying widely spatially by region), and in Canada, 4.9% share of animals and rising rapidly (displacing BA4 and 5) according to CoVariants.org

pianotuna

Regina, SK, Canada

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Posted: 10/24/22 08:50am Link  |  Quote  |  Print  |  Notify Moderator

ok ty. Is there a vax for BQ 1.1?

silversand

Montreal

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Posted: 10/24/22 09:33am Link  |  Quote  |  Print  |  Notify Moderator

....nope, not specifically the BQ.1.1 lineage (mutations ORF1b-N1191S and S-R346T). Nor the BQ.1.4 (England and Denmark, defined by S-R190T).

But as always, consult your physician for vaccine options.

* This post was edited 10/24/22 10:38am by silversand *

BCSnob

Middletown, MD

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Posted: 10/24/22 12:04pm Link  |  Quote  |  Print  |  Notify Moderator

pianotuna wrote:

ok ty. Is there a vax for BQ 1.1?


No vaccine has been developed (reported) with a more recent variant than BA.4/5.

One can get a sense of how protective the new bivalent (Wuhan + BA.4/5) vaccine from Moderna will be against a range of new variants by looking at the relative pseudovirus neutralization assay results for plasma from vaccinees (3 doses) who had BA.5 breakthrough infection. There was a 6.7x decrease in "protection" against BQ.1.1 as compared to protection against BA.5.

See Figure 2f of:

Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution
BioRxiv Preprint 4 Oct 2022

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